Uncovering Unexploited Ligases & Utilizing New Ligand Screening Technologies to Mediate Degradation

11-13 April, 2023 | Boston, MA

Welcome to the 3rd Annual Ligase Targeting Drug Development Summit

From discovery to clinical development, the field of protein degradation is booming with excitement, with a whole host of investments and new companies joining the effort to successfully degrade unwanted or undrugged targets with key roles in a broad range of diseases from oncology to CNS, through to autoimmune.

Despite this, key challenges remain to rapidly and successfully discover novel and underexploited Ubiquitin E3 ligases. It is now critical that we fully understand the structure and function of E3s and accelerate ligand screening with new and improved tools to make this process less lengthy and risky for biopharma.

The 3rd Annual Ligase Targeting Drug Development Summit is returning with fresh understandings and data from the forerunners of the field and those who have recently joined the space. Together we will investigate ligase structural and functional biology, screening tools for optimal ligase and ligand identification, and uncover the novel assays that are aiding validation.

This dedicated forum will provide an unrivaled meeting point for industry leaders to strategically accelerate and de-risk the process of identifying, validating, and therapeutically leveraging cell and tissue-specific Ubiquitin E3 ligases for degradation or modulation of targets of interest.

Key Speakers for 2023

Typical Attending Companies

What Do Previous Attendees Have To Say?

"The Summit provided a great indication of where the ligase field is. The panel discussions were particularly useful in pinpointing where our community’s challenges are”

Richard Feldman, Senior Director – Protein Sciences,
NGM Biopharmaceuticals

"It was very engaging, and I gained valuable new insights in every session"

Monica Rodrigo-Brenni, Senior Scientist

2023 Sponsors

NEOSphere Biotechnologies Logo_clear

Download the 2023 Full Event Guide